The Great Lakes Shrine Association is made up of 23 Centers in five states and the Canadian Province of Ontario. An Annual business meeting is held each February. A ceremonial session is conducted each September and is attended by thousands of Nobles from the member Shrine Centers.
Inter-Center relationships are maintained throughout the year through correspondence and other contacts, resulting in a high degree of Shrine achievement in the Great Lakes Region.
The following is a list of GLSA member Centers, and their home cities.
| Ahmed | Marquette | MI |
| Ainad | East St. Louis | IL |
| Aladdin | Columbus | OH |
| Al Koran | Cleveland | OH |
| Ansar | Springfield | IL |
| Antioch | Dayton | OH |
| Elf Kurafeh | Saginaw | MI |
| Hadi | Evansville | IN |
| Medinah | Addison | IL |
| Mizpah | Fort Wayne | IN |
| Mocha | London | ON |
| Mohammed | Peoria | IL |
| Moslem | Detroit | MI |
| Murat | Indianapolis | IN |
| Orak | Hammond | IN |
| Saladin | Grand Rapids | MI |
| Syrian | Cincinnati | OH |
| Tadmor | Akron | OH |
| Tebala | Rockford | IL |
| Tripoli | Milwaukee | WI |
| Zenobia | Toledo | OH |
| Zorah | Terre Haute | IN |
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